Abstract: Tuyuke oilfield is characterized by deep burial, high crude viscosity and poor physical properties ofreservoir. There is no successful precedent for its development to date in the world. In view of mechanisms of various re-covery processes applied to heavy oil field, this paper selected some development schemes for Tuyuke oilfield, and con-ducted optimization and correlation among depletion drive,waterflooding and chemical injection,including analysis ofsensitivity parameters by chemical flooding process. In addition,the productivity equations for pseudoplastic fluid isproposed based on its plastic fluid property of crude oil, which can be as guide to economical and effective developmentof Tuyuke oilfield.