Abstract: In order to further understand the factors affecting the production of coalbed methane(CBD) wells, the possible damage mechanisms in the production process of coalbed gas wells including reservoir stress sensitivity, near-bore zone damage, pulverized coal migration and pressure drop transmission are analyzed. Based on the principle of minimizing the above mechanism damages, the pressure drop rates in different stages of coalbed methane production are studied theoretically in this paper and then the optimization method of coal seam gas well drainage is put forward. The results show that in the early stage of CBM production, the appropriate increase of production rate will not cause serious stress sensitivity effect, and not only the drainage effect can be effectively improved, but the damage to near-bore areas can be decreased; in the middle-late CBM production stage, it is suggested that the occasional increase of pressure difference should be adopted to release the trapped gas and improve production. For the reservoirs producing pulverized coal easily, when the bottom pressure of the well is slightly greater than the critical desorption pressure, increasing pressure difference for rapid drainage can promote the expulsion of the produced pulverized coal and make the gas-water two phase flow area appear as soon as possible, and the aims to prevent the rapid water production from the far-end of the reservoir and to suppress the pulverized coal can be realized