Abstract: The conventional method of clastic reservoir interlayer modeling aims at simple interlayer description, which is lack of systematic understanding about remaining oil distribution. Four virtual wells are designed and stochastic and deterministic models are established for between-layer and within-layer interlayers. Reservoir numerical modeling regarding production modes of natural energy, water injection and gas injection is performed for the different models, the corresponding models are established by increasing area and expanding well numbers, respectively and comparisons of the models are carried out. The comparison results show that the result obtained from the stochastic modeling is of significant heterogeneity and large uncertainty, and the result obtained from the deterministic modeling is in accordance with the geological understanding. Different interlayer modeling methods lead to obvious differences in cognitions about the remaining oil distribution with the same production mode, and result in different controls on oil and water movement, remaining oil distribution and water injection and gas injection. During the middle-late stage of oilfield development, the geological understandings should be fully used to establish a deterministic interlayer model and a corresponding facies-controlled reservoir model, and to accurately quantify the remaining oil distribution, then providing basis for well allocation