Abstract: The Jurassic Shishugou group in Fudong slope area of Junggar basin is characterized by the development of channel-type sandbodies, which has the characteristics of “fault connected with oil source & reservoir controlled by lithology”. The production varies greatly among different sandbodies and it is difficult to predict high-yield reservoirs with conventional techniques and methods. On the basis of newly acquired “high density, wide azimuth and broadband” 3D seismic data of Wellblock Fudong-5, this paper analyzes the seismic response characteristics of channel sandstones. Firstly, the pre-stack AVO derivative attributes are used to distinguish oil and water in channel sandstones and the reservoirs are identified qualitatively; secondly, the effective porosity and permeability obtained from NMR logging are used to calculate porosity and permeability parameters comprehensively, and the correlation with the reservoir production is established; then the low-yield, medium-yield and high-yield oil layers can be distinguished in the reservoir by the geostatistical inversion and the production can be predicted quantitatively. Finally, the prediction results of high-yield reservoir can be obtained. The matching technology for predicting high-yield reservoirs of Jurassic channel sandstones in Fudong slope area has been integrated and formed, which can effectively guide the deployment of high-yield wells in the later period of the study area