Abstract: The stratum pore?plugging near wellbore found in the glutenite reservoirs in Karamay oilfield is caused mainly by clay expanding and migrating in strata, the leak?off of inflow liquids from drilling, completion and workover, or by sedimentation of heavy components of crude oil and bacterial growth, or occasionally by Jamin’s effect. Such multi?factor effects need corresponding plug?removal treatment of clay?acid coordinated with other chemicals according to the plug characters and stratum sensitivities to restore or enhance permeability,control sand, demulsify, prevent water?lock or acid?sludge in Karamay glutenite or conglomerate reservoirs