Abstract: AVO（amplitude versus offset）is a very useful oil?gas prediction method for lithologic reservoir exploration. The Toutunhe channel sand reservoir of Jurassic in Fudong area of Junggar basin is characterized by quick lateral changes and“one sand and one reservoir”, so difficult to properly predict where oil and gas are. In this paper, on the basis of seismic pre?stack gather forward modeling and fluid replacement/alternation, the AVO responses from the channel sands and fluids are studied and the AVO pre?stack attributes are used for oil?gas prediction of five wells in Fudong area. The result shows very good geologic effects