Abstract: In order to research the tectonic compressional deformation and its main controlling factors of salt structures in Kelasu structural belt of Kuqa depression, the paper simulates the salt tectonic deformation process of the 3 major seismic sections of Awat, Dabei and Keshen segments by using discrete element numerical simulation method. The simulation results show that the salt bed exhibits plastic deformation under the compressional setting and has relatively strong fluidity. Post-salt, salt and pre-salt beds show some structural characteristics of overall compression and layered deformation. A series of NS trending thrust structures are developed in pre-salt beds, and fault propagating folds and detached deformation structures are developed in post-salt beds. Pre-existing fractures mainly control pre-salt tectonic deformation and stress propagation range, pre-existing salt diapirs mainly influence the tectonic uplifting range of post-salt beds; salt rock distribution and palaeohigh of basement mainly impact the tectonic deformation of post-salt beds. The study results reveal the dynamic evolution process of salt structures in Kelasu structural belt, which will benefit to improve the understandings on salt tectonic deformation mechanism and its evolution process.