Abstract: Based on the drilling, seismic data, this paper analyzed the reservoir characteristic and its seismic response characterisitc in order to find out the inner dolomite reservoir distribution in eastern Maigaiti slope in Taxinan depression of Tarim basin. The result shows that fractured?vugging reservoirs are widely developed in the inner dolomite in this area, with beads?like strong amplitude anomalies on the seismic profile, and controlled by faults and fractures formed from tectonism. The seismic prediction result indicates that the inner dolomite reservoirs are widely stellate distributed in the south slope of Mazatag structural zone in eastern Maigaiti slope. There are good comparability among such dolomites and Tazhong and Gucheng areas in terms of developed horizon, reservoir type, reservoir?cap rock assembly and seismic response, etc, which could be regarded as a breakthrough target for oil and gas discovery in Maigaiti slope area