Abstract: Regarding the characteristics such as complex spatial structure, large stratigraphic dip angle, low level of well control of buried-hill dolomite reservoir and its interlayers in the Block YM32 of Tarim basin, the paper classifies the interlayers in individual wells and establishes the stratigraphic framework by calculating true formation thickness; analyzes the relationships between various seismic attributes and zones with different lithologies by using dolomite lithofacies identification technology and multiple regression mehtod, and establishes a lithofacies model for dolomite with rock texture number and multiple seismic attribute constraint; builds a 3D attribute model for the study area through stacking actual measured core porosity and permeability, and inversion attributes of seismic porosity. The fitting ratio of numerical simulation results to the well production performance is more than 93.6%, providing effective basis for remaining oil distribution description, new-well placement and existing-well stimulation in the study area.