Abstract: In order to expand the prospecting achievements in Cretaceous strata of Shinan area in Junggar basin, stratigraphical classification and hydrocarbon accumulation condition analysis are re-performed for Qingshuihe formation by the comprehensive use of seismic forward modeling, seismic inversion and seismic attribute etc. Both sedimentary cycle and logging curve are used to determine the marker bed, based on which a unified framework of the whole area is established through the integration of well logs and seismic data, and the ancient landform during the deposition of the first member of Qingshuihe formation is characterized. Gullies developed in Shinan area control the distribution of sedimentary facies and good-quality reservoirs are found in the down-incised scour channels. Reservoir prediction and hydrocarbon detection can prove that good-quality reservoir with a floor is the first condition for oil and gas accumulation and oil-bearing sandbody is the favorable target for drilling. Multiple favorable targets are determined by using density inversion and seismic attribute fusion methods, which reveals the good oil and gas exploration prospects in the area.