Abstract: The Silurian Kepingtag formation in Tazhong area in Tarim basin belongs to littoral facies sediment, and its target intervals are characterized by low?porosity and low?permeability, great lateral changes and thin mudstone interlayer and sand body. The burial depth of reservoir ranges from 5 500 m to 6 000 m. Because of absorption and attenuation, the resolution of seismic data is relatively low, resulting in difficult reservoir prediction. This paper adopts such techniques as frequency extension processing, amplitude attribute analysis, instantaneous phase and wave impedance inversion, based on the mudstone cap?rock thickness and wave impedance that normally higher than underlying sandstone reservoir, gets good results for reservoir prediction