Abstract: The deep-burial fractured sandstone reservoir in Kuqa depression has experienced strong compressional structure deformation, which is characterized by high magnitude of in-situ stress, strong anisotropy and widely developed of natural fractures. The in-situ stress on natural fracture surface seriously impacts the permeability and fluid flowing in the reservoir. To optimize fracturing stimulation program for gas wells，a research on fracability evaluation is conducted in terms of four geomechanics parameters including in-situ stress, shear-to-effective normal stress ratio on natural fracture, rock brittleness and fracture toughness for the deep-burial fractured sandstone reservoir in Kuqa depression. Based on rock mechanics testing, stress field modeling and analysis of the influence of shear deformation ability of natural fractures on gas well performance after fracturing, a fracability index evaluation model suitable for the fractured tight sandstone with high stress is established. Compared with other fracability models based on rock brittleness and fracture toughness, the new model considers the influences of present in-situ stress and natural fracture on fracturing effect, which is more sensitive to the well-to-well and layer-to-layer fracabilities in the fractured tight reservoir with strong stress, and can be used to optimize fracturing interval, determine perforation location, select injection pressure and optimize pump injection procedure, etc. The fracability evaluation technology has been successfully applied in 30 gas wells in Kuqa depression, which provides basis for quantitative fracturing program optimization in the gas wells which need to be stimulated